Alpha-lipoic acid is involved in glucose and lipid metabolism and manages gene transcription. ALA also acts as an antioxidant, because it rebuilds internal antioxidant systems and supports their production or cell availability
Essence ALA is a dietary supplement in the form of capsules containing alpha-lipoic acid (ALA) in the amount of 500 mg in the portion of the product recommended for consumption during the day.
Meet our next product - ALA, or alpha-lipoic acid (or also alpha-lipoic acid). Do you already know what this relationship is and what tasks it performs in our body?
Alpha-lipoic acid (ALA) is an organosulfur compound (contains sulfur) commonly found in cellular mitochondria. It is necessary for various enzymatic functions. It occurs in nature - it can be found in organisms of plants, animals and humans. Although ALA is synthesized (from cysteine and fatty acids) by the human body in small amounts, the amounts produced are not sufficient to meet the cell's energy needs. Therefore, there is a need to supplement it from exogenous sources. So it is mostly obtained from the diet, especially meat and vegetables. The source of this acid is also fruit. Alpha-lipoic acid is present in many vegetables (spinach, broccoli, tomatoes, Brussels sprouts and rice bran), meat and offal (e.g. liver and kidneys) in the form of lipolysis (ALA with lysine-binding residues) (1).
Although alpha-lipoic acid is available from common dietary sources, ALA is unlikely to be consumed significantly in a typical Western diet. It is dietary supplements, the serving size of which usually ranges from 50 to 600 mg, that is the main source of ALA, and most of the information on its bioavailability comes from scientific studies where supplements have been used (2). The daily portion of Essence ALA that we suggest to you contains 500 mg of alpha-lipoic acid in the portion recommended for consumption during the day.
This is not easy to explain, it is about operating at the cellular level. In the Krebs cycle, ALA plays an important role in a variety of chemical reactions, acting as a cofactor for certain enzyme complexes involved in energy production for the cell. It also forms covalent bonds with proteins. Alpha-lipoic acid is also involved in glucose and lipid metabolism and manages gene transcription. ALA also acts as an antioxidant, because it rebuilds internal antioxidant systems and supports their production or cell availability. The most unique feature of ALA compared to other antioxidant substances is that it reacts as both a lipid-soluble compound and a water-soluble compound (1).
Alpha-lipoic acid is soluble in both the water and the fatty environment. Thanks to this, it can simultaneously protect the lipid membranes of cells, as well as the intercellular spaces into which water-soluble ingredients penetrate. Both ALA and its reduced form called dihydrolipoic acid (DHLA) have antioxidant properties. ALA and DHLA have features that include the ability to react with free radicals and chelate transition metal ions, the ability to interact with other antioxidants, participate in gene expression, as well as, among others, easily absorbed from the diet (3).
Essence ALA - is perfect if you want to supplement your diet with alpha-lipoic acid.
Literature:
Salehi B., Berkay Yılmaz Y., Antika G., Boyunegmez Tumer T., Fawzi Mahomoodally M., Lobine D., Akram M., Riaz M., Capanoglu E., Sharopov F., Martins N., Cho W. C., Sharifi-Rad, J., Insights on the Use of α-Lipoic Acid for Therapeutic Purposes. Biomolecules, 2019, 9 (8), 356.
Shay K. P., Moreau R. F., Smith E. J., Smith A. R., Hagen T. M., Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential. Biochimica et Biophysica Acta, 2009, 1790 (10), 1149-1160.
Skorupa A., Michalkiewicz S., Jakubczyk M., Highly sensitive determination of α-lipoic acid in pharmaceuticals on a boron-doped diamond electrode. Open Chemistry, vol. 19, no. 1, 2021, pp. 843-854.
| Porcja: | 2 kaps. |
| Ilość porcji w opakowaniu: | 45 |
| Opakowanie: | 90 kaps. |
| Mass net: | 78.30 g |
| Wartość odżywcza / Informacja żywieniowa | ||
| na 2 kaps. | % RWS* | |
| Kwas alfa-liponowy | 500 mg | - |
Alpha-lipoic acid is involved in glucose and lipid metabolism and manages gene transcription. ALA also acts as an antioxidant, because it rebuilds internal antioxidant systems and supports their production or cell availability